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Microbiome Labs MegaSporeBiotic Daily Probiotic

Microbiome Labs MegaSporeBiotic Daily Probiotic

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  • 100% Spore-Based Probiotic for Microbiome Support- MegaSporeBiotic uses spore-based probiotic strains to recondition the gut microbiome, promoting microbial diversity and gut health support for women and men. Supports digestive function and immune resilience.*
  • DNA-Verified Bacillus Strains for Digestive Health - Features clinically studied strains: B. subtilis, B. indicus, B. clausii, B. licheniformis, and B. coagulans. Start with ½ to 1 capsule with food, then gradually increase to 2 capsules daily, or as directed by your practitioner.*
  • Probiotic That Survives Digestion and Colonizes Intestine - Spore-forming bacillus probiotics survive stomach acid and activate in the intestines. Designed to support bloating relief for women and men, microbial balance, and long-term digestive health without refrigeration.*
 

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Week 1: 1 capsule every other day.

Week 2: 1 capsule per day.

Week 3+: 2 capsules per day, with food, or as recommended by your healthcare practitioner.

If you are pregnant or nursing, taking any medication, or have a medical condition, always consult your doctor before using this product. Keep out of reach of children. Do not use if safety seal is broken or missing. No refrigeration required.

  • Bacillus Indicus HU36

    Produces vitamins and carotenoids, including astaxanthin,zeaxanthin, and a-carotene.

  • Bacillus subtilis HU58

    Secretes antimicrobial compounds, supports healthy liver function, and produces nattokinase and vitamin K2.

  • Bacillus clausii SC-109

    known for supporting a strong and balanced immune system.

  • Bacillus coagulans SC-208

    Produces L+ lactic acid to support immune and gut defense and promotes B-galactosidase (lactase) activity to aid lactose breakdown.

  • Bacillus licheniformis SL-307

    Aids protein digestion and B-vitamin synthesis.

    A smarter way to support gut health

    100% spore-based probiotic

    Supports gut reconditioning*

    Clinically tested to maintain a healthy gut microbiome*

    • Vegan/Vegetarian

    • Non-GMO

    • Gluten-Free

    • Free From 9 Major Allergens

    • Made In The U.S.With Globally Sourced Ingredients

      Meet Mega SporeBiotic

      100% spore-based, 5-strain probiotic designed to survive the journey through digestion.Resilient Bacillus spores help support a healthy gut barrier, promote microbial diversity, and fuel a more balanced, resilient gut microbiome.

      SHOP NOW

        Better research.Real results.

        Mega SporeBiotic provided relief for occasional abdominal discomfort and supported elimination and digestive health in study subjects.

        Ten peer-reviewed studies

        found that Mega SporeBiotic promotes:

        Greater microbial diversity*

        Health-supportive gut bacterial growth (and thus, short-chain fatty acid production)*

        Helps maintain a healthy balance of naturally occurring flora*

        Robust whole body benefits

        Promotes microbial diversity*

        Antioxidant producing*

        Supports the gut barrier/lining*

        Promotes immune function*

        The spore advantage

        Bacillus spores stay dormant in harsh conditions, then activate where they're needed.

        • Dormant

          Protected by a natural spore shell, they survive stomach acid, heat & shelf storage

        • Active

          Reach the intestines and shift to their active,vegetative form

        • Recondition

          Promote microbial diversity & key species with high survivability

            Others
          STRAIN RESILIENCE
          EXCEPTIONAL SURVIVAL
          QUORUM SENSING MODE OF ACTION
          MICROBIOME RECONDITIONING
          REAL WORLD EVIDENCE (300 PARTICIPANTS)

          5 researched bacillus strains to support:

          Microbial diversity*
          Antioxidant production*
          Gut barrier strength*
          Immune function*

          Backed by 10 clinical studies

          In 60 days, Mega SporeBiotic provided relief for occasional abdominal discomfort and supported elimination and digestive health.

          FAQs

          Are Microbiome Labs products third-party tested and independently verified?

          Microbiome Labs follows quality and testing protocols to help ensure products meet label claims and quality standards.

          What is the science behind Microbiome Labs products?

          We pride ourselves on the scientific backing of our products. MegaSporeBiotic alone has 10 human clinical trials on the finished formula. We conduct Real World Evidence studies on our finished products, and our ingredients are some of the most studied probiotics in the world. As part of the Novonesis family, we have access to well-researched bacterial strains and feature them in almost all our formulas.

          What is the difference between a probiotic, prebiotic, and digestive enzyme?

          Probiotics are beneficial microorganisms. Prebiotics are fibers or compounds that help nourish beneficial microbes. Digestive enzymes help break down food components like proteins, fats, and carbohydrates to support digestion. Many people use them together depending on their goals, diet, and sensitivity.

          Are your products gluten free?

          Gluten free status varies by product. Check the label and product page for gluten free statements and ingredient disclosures. If you have questions, talk to your healthcare provider.

          What is the shelf life of your products?

          Shelf life varies by product. You'll find a "Best by" date printed on every bottle or package. Most of our products have a 24-month shelf life from the date of manufacture. Store them as directed on the label to maintain freshness and potency through that date.

          What makes MegaSporeBiotic different from traditional probiotics?

          Traditional probiotics rely on fragile strains that are sensitive to heat, moisture, and stomach acid. MegaSporeBiotic™ is a spore-based probiotic. It uses spore-forming strains chosen for their resilience and compatibility with the digestive environment, so beneficial microbes can reach the gut and support a balanced microbiome.

          Are probiotics safe to take during pregnancy and breastfeeding?

          In general, probiotics are widely used, but pregnancy and breastfeeding are unique physiological states. It’s best to consult your OB/GYN, midwife, or healthcare provider before starting any supplement to ensure it’s appropriate for your individual needs.